Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
The American Film Institute has picked its 10 best movies and TV shows of the year. The titles, presented in alphabetical order, are works AFI's juries have determined advance the art of the moving image, enhance the cultural heritage of America's art form, inspire audiences and artists and make a mark on American society.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
China has all long and continues to support a united, prosperous and stable European Union, support a strong Euro, and support European integration process. We believe that is good for globalization, for a multipolar world and for diversity of civilizations. We feel optimistic about the future of the EU and the future of China-EU relations.
But if the U.S. can avert that Washington-made crisis, the outlook for workers finding jobs is actually looking pretty good for next year. For one thing, the damage of superstorm Sandy will have to be repaired, meaning jobs in construction and retail. Businesses, meanwhile, which have held off investing and hiring because of uncertainty over the fiscal outlook, might finally open their wallets. That means more jobs, too.[qh]
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
We learned about fetal surgery’s potential to change lives.
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
We asked FlightAware to look at arrival delays, rather than departure delays, because it is sometimes possible for airlines to make up time lost on the ground while the plane is in the sky.
Trends and targets in antiviral phototherapy
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
"The scenes in the TV adaptation are beautiful, and also consistent with the original work," a Douban user Banchengyansha said.
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
In response, Mr Wilders labelled Mr Rutte a liar, citing the prime minister’s broken pledge not to support a bailout of Greece during the 2012 election.
5.Create a Study Space
ACE2 as a potential therapeutic target for pandemic COVID-19
Diagnostic technologies for COVID-19: a review
What’s more, in recognition of their working on the bizarre properties of matter in extreme states and taking their research all the way down to an atomic scale, the Nobel Prize for physics was awarded to three British-born scientists who currently work in the US.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
"The online Internet anti-corruption bid mostly relies on text, photos and videos and it is easy to be superficial if corrupt officials are only exposed this way."
Am I tempting fate by wondering if the Lakers end up in this conversation within a couple weeks? They'd have to go on a truly epic slide to be bad enough to keep their draft pick at this rate (top-three protected to Philly) but I think the question is whether they should continue to build slowly around this core or flip one or two of the young dudes for a star.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
I'm sure Dwight Howard's never used steroids, but it sure looks like he has. It looks like Howard doubled in size since leaving high school for the NBA.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
My Sunshine is a TV drama adapted from Gu Man`s novel of the same title. It stars Wallace Chuang and Tang Yan, premiering in January, 2015. The drama depicts a man and a woman`s reunion and long-lasting romance after seven years of separation. The novel itself has been popular on the Internet and was published in 2003. Wallace Chuang soon rose to become a romantic icon among female viewers because of the role he played in the adaptation, presenting an ideal image of lover to the audiences.
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Today, the Financial Times reveals the fake gross domestic product data routinely released from many northern Chinese regions. There, solid alternative evidence suggests the authorities have “smoothed” the economic growth figures. They artificially boosted growth figures between 2012 and 2016, masking a real downturn, and last year covered up a genuine recovery.
Antiviral drug discovery: broad-spectrum drugs from nature
Golden State equaled the 1957-58 Celtics as the only defending champions to win their initial 14 games. The Warriors are one of five teams in NBA history to begin 14-0, and will travel to Denver looking to keep it going Sunday.
Influenza neuraminidase: A druggable target for natural products
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Meanwhile, in an unfortunate red carpet faux pas, Pink and Shakira both showed up in the same Balmain dress.
We will endeavor to transform and upgrade traditional industries.
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
One of the most discouraging aspects of 2014 for professional investors has been the start-and-stop nature of the recovery. We coasted into January on a trend of strengthening economic reports. Within a few weeks, a nationwide snowstorm seemingly drove the economic data off the side of the road.
At age 20, the teen prodigy of "Royals" raised the bar, marrying the massive vistas of electronic music alongside the human-scaled and handmade on her second LP, with help from co-producer Jack Antonoff.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
"What China is lacking is not legislation but strict enforcement."
More provinces are falling in situations where the pension fund cannot cover the expenditures. As one of six provinces with the problem last year, Heilongjiang's enterprises pension can only pay up to one month.
*剧情类最佳客串女演员：玛格?马丁戴尔(Margo Martindale)，《美国谍梦》(The Americans)
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Russia's economy is the 10th largest in the world, producing little of value beyond hydrocarbons. Corruption and rent-seeking extract an enormous economic toll. It remains burdened with Soviet era infrastructure, and its ability to meet the educational and medical needs of its population is rapidly declining.
Businesswomen are booming in Asia: The whole region makes a strong showing, from China and Singapore to New Zealand and Thailand. Entrepreneurship is on the rise: see Zhang Xin (No. 50) , Sun Yafang (No. 77) and Solina Chau (No. 80). And Asian region women are showing their political might, from newcomer Park Geun-hye, the South Korean president (No. 11) and Burmese dissident and parliamentarian Aung San Suu Kyi (No. 29) to Australian PM Julia Gillard (No. 28) and Thai Prime Minister Yingluck Shinawatra (No. 31).
Inhibition of SARS coronavirus helicase by bismuth complexes
In total, Chinese mainland has 54 institutions in the listing of top 300 universities in Asia.
China has recently made majordecisions about its economic future. On November 15, 2013, China announceddramatic new social and economic policies contemplating much greater relianceon market forces than it has in the past and inviting private-sectorparticipation and foreign competition in industries long previously controlledby the central government. It also relaxed its one-child policy, openingthe country and its people to vast new opportunities and inspiring new hopes anddreams.
Landing a superstar like Cousins for pennies on the dollar won't singlehandedly help the Pelicans carve out a larger slice of the sports landscape in New Orleans, but it's an excellent first step.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Warm greetings and best wishes for the New Year!致以热烈的祝贺和良好的祝福,新年快乐。
The fastest growing start-ups tend to be global in their outlook. The immigration restrictions already imposed by President Trump in the US and those under consideration as part of the UK’s separation from the EU are likely to be a hindrance in the coming year for hiring.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
On Sunday, the night before the Doodle debuted, Zhang told Newsday she was "excited" by the big win, but said she wouldn't be awake when her art first went online at midnight.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Will oil finish 2018 above $70 a barrel
Foreign property investment by Chinese companies plunged by 84 per cent last month, as Beijing’s capital controls choked off the flow of foreign acquisitions.
We will perform with a strong work ethic, sense of responsibility, and enterprising spirit.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Now a white-haired grandfather, Belmonte has never regretted missing the 1950 match, particularly since his mother died just a few days later. "I decided not to go, and it was a good decision," he told the reporters.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
STEP 5: GET RID of most of your friends
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
A video of Bi Fujian, a popular television host, poking fun at a song from a Cultural Revolution-era opera about the Chinese civil war, with his own critical asides about Mao and the Communist Party, appeared online in April. Despite the government's efforts to contain its spread, it circulated widely, with some commenters defending Mr. Bi's opinions and his right to express them.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
"If reform implemented 30 years ago solved the problem of ideology, then, at present, reform is to solve the problem of interests. Reform at present is actually like cutting our own with a knife, and we all need to be determined and must strengthen our confidence." WANG YANG, NPC deputy and member of the Political Bureau of the Communist Party of China Central Committee
In 2016, China's box-office experienced a shock correction, with growth plummeting to just 3.7 percent from a roaring 48 percent rate in 2015.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Whiteness means being part of the group whose appearance, traditions, religion and even food are the default norm. It’s being a person who, by unspoken rules, was long entitled as part of “us” instead of “them.”
Rihanna, who came in at second place, earned her runner-up position "following another 12-month period in which she was absolutely bloody everywhere and yet we all entirely failed to get sick of her," per FHM.
UK schools account for more than a third of all graduates from the top 50 pre-experience programmes and not only attracted nearly half of all female students but also almost half of all international students. Indeed, 94 per cent of students enrolled in a UK MiF pre-experience programme in 2014 were from overseas. About 85 per cent of these students were from outside the European Economic Area, including 55 per cent of the overall number from mainland China.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The Warriors and Timberwolves will arrive in Shenzhen on Oct 5 and will play at the Shenzhen Universiade Center.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Employers have stepped up their hiring recently, adding 171,000 jobs in October and an average of 157,000 a month so far this year. That's a better pace than last year and the strongest job growth since 2006, Labor Department data show.[qh]
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Rihanna vs. Rosario Dawson Both stars wore this long satin Dolce & Gabanna dress in different colors. 蕾哈娜和罗莎里奥·道森都穿了这件款式一致颜色不同的D&G
A modular microarray imaging system for highly specific COVID-19 antibody testing
THE BRIDGE (Hulu, Friday) The second season of this Danish-Swedish crime drama (the source for FX’s recently canceled series of the same name) once again involves the Oresund Bridge connecting the two countries.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Warm greetings and best wishes for the New Year!致以热烈的祝贺和良好的祝福,新年快乐。
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Good luck, good health, hood cheer. I wish you a happy New Year.
虽然汉德曾在英国石油公司（British Petroleum）担任过多年全球品牌、营销与创新高级副总裁，但她现在却在从事更加环保的事业。Project Frog的使命是希望通过易于建造的空间（通常几天或者几个月便可完成），彻底改造建筑行业。相比教育与医疗等行业的传统建筑，Project Frog的建筑可以节省约50%的能源。汉德的计划似乎已经奏效：公司今年的收入预计将增加一倍以上。
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A facile assay for rapid detection of COVID-19 antibodies
Best chances: Sally Hawkins is only a fraction behind current best actress favorite Frances McDormand.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
陆金所是最大的一家。它是中国平安保险(Ping An Insurance)的子公司，平安也是陆金所最大的股东。
France’s HEC Paris and Essec Business School remained second and third, respectively, for the third year running.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
I wish you a happy New Year. All affection and best wish
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
After years working with large consumer product companies like Stride Rite and Keds, Pieri grew frustrated with the difficulty mom-and-pop shops had launching new products. "The more innovative a product—as opposed to mainstream and "known"—the harder it was to get distribution," she explains. In response, she launched The Grommet, a discovery platform that connects customers with inventors' stories and their products, five years ago. Pieri, whose company helped launch products including SodaStream and Fitbit, counts HP CEO Meg Whitman as a mentor and has a side-gig as an entrepreneur in residence at Harvard Business School.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Some 88 Chinese universities are included in the Global 400 subjects in the latest QS World University Rankings by Subject, which was released Tuesday by QS Quacquarelli Symonds, a higher education research firm.
Anti-HIV drug repurposing against SARS-CoV-2
剧情类最佳剧集：《权力的游戏》(Game of Thrones, HBO)
Length-scale dependence of protein hydration-shell density
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
The Producer Price Index (PPI), which gauges factory-gate prices and is a major indicator of economic briskness, rose by 6.3% in 2017, compared with a minus 1.4% for 2016, reversing the trend of continual decline since 2012.
18. 最有趣的道歉（并列）。11月18日，《好莱坞报道者》发表了一份1200多字的道歉，因为它的“奥斯卡女星圆桌会议”没有邀请非白人演员出席。很快，导演亚历克斯·普罗亚斯(Alex Proyas)和狮门公司就为新片《埃及众神战》(Gods of Egypt)中的演员缺乏多样性而道歉。
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12306.cn, China's official website for purchasing railway tickets, has become the largest of this kind in the world, with combined sales reaching 3.5 billion in 2017.